ROSACEA KERATITIS

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ROSACEA KERATITIS is defined as : Corneal ulceration is seen in about 10 percent cases of acne rosacea, which is primarily a disease of the sebaceous glands of the skin.

Clinical features
1. The condition typically occurs in elderly women in the form of facial eruptions presenting as butterfly configuration, predominantly involving
the malar and nasal
area of face.

2. Ocular lesions include chronic blepharo conjunctivitis and keratitis. Rosacea keratitis occurs as yellowish white marginal infiltrates, and small ulcers that progressively advance across the cornea and almost always become
heavily vascularised.

Treatment
1. Local treatment. Rosacea keratitis responds to topical steroids, but recurrences are very common.

2. Systemic treatment. The essential and most effective treatment of rosacea keratitis is a long course of systemic tetracycline 
(250 mg QID × 3 weeks, TDS × 3 weeks, BID × 3 weeks, and oncea day for 3 months).

CORNEAL ULCER ASSOCIATED WITH
SYSTEMIC COLLAGEN VASCULAR DISEASES
Peripheral corneal ulceration and/or melting of corneal tissue is not infrequent occurrence in patients suffering from systemic diseases such as rheumatoid arthritis, systemic lupus erythematosus, polyarteritis nodosa and Wegener's granulomatosis. Such corneal ulcers are usually indolent and difficult to treat. Systemic treatment of the primary disease may be beneficial.