MOOREN'S ULCER

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The Mooren's ulcer (chronic serpiginous or rodent ulcer) is a severe inflammatory peripheral ulcerative keratitis.

Etiology
Exact etiology is not known. Different views are :
1. It is an idiopathic degenerative conditon.
2. It may be due to an ischaemic necrosis resulting from vasculitis of limbal vessels.
3. It may be due to the effects

ROSACEA KERATITIS

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ROSACEA KERATITIS is defined as : Corneal ulceration is seen in about 10 percent cases of acne rosacea, which is primarily a disease of the sebaceous glands of the skin.

Clinical features
1. The condition typically occurs in elderly women in the form of facial eruptions presenting as butterfly configuration, predominantly involving
the malar and nasal

EXPOSURE KERATITIS

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Normally cornea is covered by eyelids during sleep and is constantly kept moist by blinking movements during awaking. When eyes are covered insufficiently by the lids and there is loss of protective mechanism of blinking the condition of exposure

Treatment of corneal ulcer

 corneal ulcer treatment

[A] Clinical evaluation
Each case with corneal ulcer should be subjected to:
1. Thorough history taking to elicit mode of onset, duration of disease and severity of symptoms.

2. General physical examination, especially for built, nourishment, anaemia and any immunocompromising disease.

3. Ocular examination should include:
i. Diffuse light examination for gross lesions of the lids, conjunctiva and cornea including testing for sensations.
ii. Regurgitation test and syringing to rule out lacrimal sac infection.
iii. Biomicroscopic examination after staining of corneal ulcer with

corneal ulcer Complications

 Complications of corneal ulcer

1. Toxic iridocyclitis. It is usually associated with cases of purulent corneal ulcer due to absorption of toxins in the anterior chamber.

2. Secondary glaucoma. It occurs due to fibrinous exudates blocking the angle of anterior chamber (inflammatory glaucoma).

3. Descemetocele. Some ulcers caused by virulent organisms extend rapidly up to Descemet's membrane, which gives a

Hypopyon corneal ulcer "cornea"

Etiopathogenesis of Hypopyon corneal ulcer " cornea"

Causative organisms. Many pyogenic organisms (staphylococci, streptococci, gonococci, Moraxella) may produce hypopyon, but by far the most dangerous are pseudomonas pyocyanea and pneumococcus. Thus, any corneal ulcer may be associated with hypopyon, however, it is customary to reserve the

corneal ulcer Pathogenesis and pathology

Pathology of corneal ulcer Once the damaged corneal epithelium is invaded by the offending agents the sequence of pathological changes which occur during development of corneal ulcer can be described under four stages, viz., infiltration, active ulceration, regression and cicatrization. The terminal course of corneal ulcer depends upon the virulence of infecting

Pathology of sloughing corneal ulcer and formation of anterior staphyloma

When the infecting agent is highly virulent and/or body resistance is very low, the whole cornea sloughs with the exception of a narrow rim at the margin and
total prolapse of iris occurs. The iris becomes inflamed and exudates block the pupil and cover the iris surface; thus a false cornea is formed. Ultimately these exudates organize and form a thin fibrous layer over which the conjunctival or corneal epithelium rapidly grows and thus a pseudocornea is